Same Gene, Different Tissue

The same methylation change can mean different things in different tissues.

🎮
Simulation

Pick a gene and compare how the same methylation reads across brain, liver, immune and more.

Gene:
Brain
BDNF

BDNF supports neuroplasticity, mood and learning. Low expression may affect memory and resilience.

Liver
BDNF

No tissue-specific note — interpretation depends on biological context, functional demand and the tissue's regulatory pattern.

Muscle
BDNF

No tissue-specific note — interpretation depends on biological context, functional demand and the tissue's regulatory pattern.

Immune
BDNF

No tissue-specific note — interpretation depends on biological context, functional demand and the tissue's regulatory pattern.

Fat
BDNF

No tissue-specific note — interpretation depends on biological context, functional demand and the tissue's regulatory pattern.

Colon
BDNF

No tissue-specific note — interpretation depends on biological context, functional demand and the tissue's regulatory pattern.

Skin
BDNF

No tissue-specific note — interpretation depends on biological context, functional demand and the tissue's regulatory pattern.

Key lesson: The 'same' result does not mean the same thing everywhere. Tissue, context and the rest of the biochemistry matter.