Personalized Intervention Builder

Pick a goal and see foods, supplements, labs, lifestyle and biological rationale.

Goal

Lower homocysteine

Target genes / pathways
MTHFRMTRMTRRBHMTCBSPEMTSHMT1/2
Foods

Leafy greens, eggs, beets, fish, legumes, adequate protein.

Supplements
  • • 5-MTHF 200–400 mcg/day
  • • B12 500–1000 mcg/day
  • • B2 (riboflavin) 10–25 mg/day
  • • B6 / P5P 10–25 mg/day
  • • TMG 500–1500 mg/day
  • • Magnesium 200–400 mg/day
  • • Creatine 3–5 g/day
  • • Choline 250–500 mg/day
Suggested labs
  • • Homocysteine
  • • B12
  • • Folate
  • • MMA
  • • B6
  • • B2
  • • SAM:SAH if available
Lifestyle

Stable sleep, reduced alcohol, weight optimization, regular movement.

Warning

Start low if anxiety, insomnia, COMT/MAOA sensitivity or history of overstimulation.

Biological rationale

Supports folate, B12 and BHMT routes for homocysteine recycling and SAMe production.

Disclaimer · This educational tool does not diagnose, treat or cure disease. Nutrients, supplements and lifestyle interventions should be personalized according to symptoms, lab results, medications, history and professional supervision.