Deficiency Simulator

Toggle deficiencies and see exactly where the methylation pathway breaks.

“The goal is not to methylate everything. The goal is to regulate the right genes, in the right tissues, at the right time, at the right intensity.”

Missing cofactors

Affected steps

Folate cycle (5-MTHF supply)OK

Methionine cycle (SAMe production)OK

BHMT backup remethylationOK

Transsulfuration (cysteine, glutathione)OK

TET demethylationOK

SAMe100

Homocysteine25

Select one or more nutrients to see the impact.